What is omeprazole?
Omeprazole is a drug that inhibits acid production in the stomach. Medications containing omeprazole are prescribed for dogs mainly in the treatment of heartburn. This article provides comprehensive information on the topic.
What is omeprazole used for in dogs?
In dogs and cats, experience is available for the following treatments:
- Gastro-duodenal ulcers
- Reflux esophagitis
It may also be usedas adjunctive therapy in the treatment of recurrent gastric inflammation and ulceration causedby bacteria .
Dosage should always be discussed with a veterinarian and is not intended for long-term use.
How does omeprazole work in dogs?
This active ingredient is used in both humans and animals. It acts as a proton pump inhibitor, which consequently inhibits the production of stomach acid. This leads to an increase in the pH level in the stomach.
Additionally, omeprazole has been found to have cell-protective effects in addition to its acid-reducing properties by increasing prostaglandin secretion from mucosal cells.
When may omeprazole be used?
Mainly, omeprazole is used in dogs for heartburn. It is a drug with minor side effects, even at higher doses. However, this agent should not be used in the following cases:
- severely impaired (kidney and) liver function.
- for long-term use
If only liver disease is involved, or patients who have had liver disease, the advantages and disadvantages should be weighed against each other.
Are there side effects of omeprazole?
Side effects of omeprazole in dogs are rare, none have been described in detail so far. However, due to the possibility that it could be carcinogenic with long-term use , this use should be avoided.
Dosage of omeprazole
Dosage depends on several factors, such as age, weight, and breed of the dog. Oral dosage of 0.5-1 mg per kg of body weight once daily is recommended. A veterinarian should perform the dose calculation.
If one wishes to treat a bacterial infestation of Helicobacter pylori in dogs , a 10- to 14-day course of omeprazole in combination with other medications is usually prescribed.
How long and how often can I give my dog omeprazole?
Since this active ingredient can be of different types, it is necessary to read the package insert carefully. In addition, a veterinarian should always be consulted who can provide accurate information on the administration of omeprazole.
Comparison of omeprazole
At current levels, omeprazole is considered by some to be the most effective substance for reducing excessive acid production.
Alternatives for omeprazole
Another agent is cimetidine, but compared to it, omeprazole is about 30 times more effective against acid. It also has a better effect in terms of pain relief.
Sources and relevant links
Accessed on 15.08.2023
Accessed on 15.08.2023
Wolfgang Löscher, Angelika Richter, Heidrun Potschka (2014). Pharmakotherapie bei Haus- und Nutztieren. Hrsg. 9., aktualisierte und erweiterte Auflage. Enke Verlag.
Wolfgang Löscher, Angelika Richter (2016). Lehrbuch der Pharmakologie und Toxikologie für die Veterinärmedizin. Hrsg. 4., vollständig überarbeitete Auflage. Enke Verlag.